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There is troubling news for Pfizer and cancer med Xtandi, one of the assets it picked up in its $14 billion deal last year for Medivation. The drug giant and its partner Astellas have given up their trials of Xtandi in breast cancer. Xtandi, which is already approved for treating prostate cancer, is shared with Tokyo-based drugmaker Astellas....

The amyloid plaques that characterize Alzheimer’s disease are surrounded by microglia, which are neurological cells that help govern how the brain responds to injury. Now, scientists at the University of Pennsylvania have discovered three genetic variants in microglia that may enhance the immune system’s ability to fight Alzheimer’s—and that may...

What is Chronic Granulamatous Disease? CGD is a disease of the immune system. It is described as a primary immunodeficiencydisorder. “Primary” means it is not caused by some other disease or disorder.1 In people who have CGD, a type of white blood cell called a phagocyte is defective.2 These defective phagocytes cannot generate superoxide, le...

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