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Meningitis test breakthrough by Belfast scientists

Posted on over 1 year ago by Laurentina Kennedy The RFT Group 012302400

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The new test can identify potential cases of meningitis within an hour

The new test can identify potential cases of meningitis within an hour

Scientists have come up with a new test which can identify potential cases of meningitis in a fraction of the current time.

Standard tests for the meningococcal disease, which can lead to meningitis and blood poisoning, can take up to 48 hours for results to come back. 

However, a new diagnostic tool created by experts at Queen's University Belfast and The Belfast Trust can provide results within an hour.

Researchers said the test could prevent children with the meningococcal disease being wrongly sent home, potentially saving dozens of lives every year. It could also prevent children being admitted for treatment unnecessarily.

If medics suspect a child may have meningococcal septicaemia they administer antibiotic treatment straight away.

A study by the organisations found that of 105 babies and children treated for suspected meningococcal septicaemia, only a third were later found to be infected, meaning two-thirds received treatment unnecessarily.

The new diagnostic test, known as Loop Mediated Isothermal Amplification (LAMP), has been assessed in a two-year study.

Researchers said the LAMP diagnostic tool proved to be as efficient as the standard test in returning accurate diagnosis.

Dr James McKenna, clinical scientist and lead researcher in developing the LAMP test said: "The LAMP test enables doctors to efficiently diagnose meningococcal septicaemia within an hour.

"The LAMP diagnosis could significantly reduce the number of patients taking medication unnecessarily as well as preventing needless anxiety to patients and their families."

Dr Tom Waterfield is leading a new study at Queen's University in collaboration with the Paediatric Emergency Research UK and Ireland to assess the practicality of testing being undertaken by a clinician in a hospital environment.

"We know that scientifically the test is effective but we now need the evidence base to confirm whether it is feasible for clinicians to carry out this test as part of their role before an informed decision can be taken," said Dr Waterfield.

"As part of this study, we will evaluate the feasibility of clinicians using the LAMP test in a hospital setting by assessing any potential barriers and ease of use."

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